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(Circulation. 1950;1:321.)
© 1950 American Heart Association, Inc.

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Further Studies of the Cardiodynamics of Experimental Intraventricular Communications

JOHN G. HAWLEY M.D.¹; ROBERT C. LITTLE M.D.¹; HAROLD FEIL M.D.¹

¹ From the Departments of Physiology and Medicine of Western Reserve University School of Medicine, and from Lakeside Hospital, Cleveland, Ohio.

This communication deals with the altered ventricular dynamics occasioned by temporary opening of a large artificial interventricular shunt. Since the left ventricular discharge into the right ventricle begins some time after ejection of blood into the aorta, the left ventricle assists the right in propelling larger quantities of blood through the pulmonary circuit. This late systolic flow through a shunt causes characteristic deformations of central arterial pressure pulses and a midsystolic murmur similar to those observed in several clinical cases.

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