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(Circulation. 1954;10:902.)
© 1954 American Heart Association, Inc.

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The Effect of Congestive Heart Failure on Blood Volume as Determined by Radiochromium-Tagged Red Cells

SEYMOUR EISENBERG M.D.¹ MARY SUE MCCALL ¹

¹ From the Department of Internal Medicine of the Southwestern Medical School of the University of Texas, and the Medical Service and Radioisotope Unit of the Veterans Administration Hospital, Dallas, Tex.

Total blood volume, red cell mass and plasma volume have been determined with radiochromium in subjects with congestive heart failure, before and after treatment. All functions were significantly increased during the congestive state and all decreased as compensation was achieved. The magnitude of the hypervolemia and the changes incident to treatment were apparently related to alterations in heart size. Selective expansion of the plasma volume was not encountered.

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