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(Circulation. 2004;110:3781-3788.)
© 2004 American Heart Association, Inc.
Health Services and Outcomes Research |
From the Departments of Sociology (D.P.P., J.R.J.) and Mathematics (I.S.A.), University of CaliforniaSan Diego, La Jolla, the San Diego Center for Patient Safety (D.P.P.), and the Tufts Health Care Institute, Tufts University School of Medicine (R.R.P.), Boston, Mass.
Correspondence to David P. Phillips, PhD, Department of Sociology, University of CaliforniaSan Diego, La Jolla, CA 92093-0533. E-mail dphillips{at}ucsd.edu
Received September 10, 2004; revision received October 29, 2004; accepted November 2, 2004.
Background Research published in Circulation has shown that cardiac mortality is highest during December and January. We investigated whether some of this spike could be ascribed to the Christmas/New Years holidays rather than to climatic factors.
Methods and Results We fitted a locally weighted polynomial regression line to daily mortality to estimate the number of deaths expected during the holiday period, using the null hypothesis that natural-cause mortality is unaffected by the Christmas/New Years holidays. We then compared the number of deaths expected during the holiday period, given the null hypothesis, with the number of deaths observed. For cardiac and noncardiac diseases, a spike in daily mortality occurs during the Christmas/New Years holiday period. This spike persists after adjusting for trends and seasons and is particularly large for individuals who are dead on arrival at a hospital, die in the emergency department, or die as outpatients. For this group during the holiday period, 4.65% (±0.30%; 95% CI, 4.06% to 5.24%) more cardiac and 4.99% (±0.42%; 95% CI, 4.17% to 5.81%) more noncardiac deaths occur than would be expected if the holidays did not affect mortality. Cardiac mortality for individuals who are dead on arrival, die in the emergency department, or die as outpatients peaks at Christmas and again at New Years. These twin holiday spikes also are conspicuous for noncardiac mortality. The excess in holiday mortality is growing proportionately larger over time, both for cardiac and noncardiac mortality.
Conclusions Our findings suggest that the Christmas/New Years holidays are a risk factor for cardiac and noncardiac mortality. There are multiple explanations for this association, including the possibility that holiday-induced delays in seeking treatment play a role in producing the twin holiday spikes.
Key Words: epidemiology mortality heart diseases patients holidays
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