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(Circulation. 1956;14:212.)
© 1956 American Heart Association, Inc.

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Quantitative Estimation by Indicator-Dilution Technics of the Contribution of Blood from Each Lung to the Left-to-Right Shunt in Atrial Septal Defect

H. J. C. SWAN M.B.¹; PETER S. HETZEL M.D.¹; EARL H. WOOD M.D.¹

¹ From the Mayo Clinic and the Mayo Foundation, a part of the Graduate School of the University of Minnesota, Rochester, Minn.

A method based on the initial portion of indicator-dilution curves has been used to determine the proportion of blood from each lung which drains anomalously. The results obtained appear to substantiate the derivation and permit the expression, in numerical values, of the greater proportion of anomalous drainage of blood from the right lung in the usual case of atrial septal defect. The principal assumptions pertaining to the method are discussed in some detail.