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(Circulation. 1957;15:865.)
© 1957 American Heart Association, Inc.

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Stenosis of a Branch of the Pulmonary Artery

An Additional Cause of Continuous Murmurs over the Chest

FREDERIC ELDRIDGE M.D.¹; ARTHUR SELZER M.D.¹; HERBERT HULTGREN M.D.¹

¹ From the Department of Medicine of the Stanford University School of Medicine, San Francisco, Calif.

Three patients have been demonstrated by cardiac catheterization to have stenosis of a main branch of the pulmonary artery. Two exhibited continuous ductus-like murmurs at the chest wall over the site of stenosis. Demonstration of a pressure gradient throughout the cardiac cycle at the site of stenosis in these 2 patients and the experimental production in the dog of a continuous murmur at the site of partial constriction of a pulmonary artery prove that the murmur is due to the stenosis. This anomaly should be added to the differential diagnosis of continuous murmurs over the chest.

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