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(Circulation. 1958;17:232.)
© 1958 American Heart Association, Inc.

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Patent Ductus Arteriosus in Association with Pulmonic Stenosis

A Report of Six Cases with Additional Noncardiac Congenital Anomalies

DOUGLAS C. HEINER M.D.¹ ALEXANDER S. NADAS M.D.¹

¹ From the Department of Pediatrics, Harvard Medical School and the Sharon Cardiovascular Unit, Children's Medical Center, Boston, Mass.

A review was made of patients recently seen at the Children's Medical Center, Boston, who qualified for the diagnosis of patent ductus arteriosus associated with pulmonic stenosis. Six such patients were observed. The cardiac findings were distinctive, allowing for presumptive diagnosis without catheterization in the majority of instances. Noncardiac congenital anomalies of a particular type were found to be a part of the clinical profile. This finding plus certain epidemiologic evidence suggests the possibility of a common etiologic factor.