This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via Google Scholar Google Scholar Articles by SPRITZ, N. Articles by RUBIN, A. L. Search for Related Content PubMed PubMed Citation Articles by SPRITZ, N. Articles by RUBIN, A. L.

(Circulation. 1959;19:600.)
© 1959 American Heart Association, Inc.

---

Osmole and Water Excretion in Mercurial Diuresis in Congestive Heart Failure

NORTON SPRITZ M.D.¹; GEORGE W. FRIMPTER M.D.¹; WARREN S. BRAVEMAN M.D.¹; ALBERT L. RUBIN M.D.¹

¹ From the Cardio-Renal Laboratories, Second (Cornell) Medical Division, Bellevue Hospital and the Department of Medicine, Cornell University Medical College, New York, N. Y.

The relationhip between water and total solute excretion following mercurial administration has been previously studied in normal human subjects during superimposed water and solute diureses. It is the purpose of the study to determine the solute/water relationships in the mercurial diuresis produced in water-deprived patients with edema from congestive heart failure. The results indicate that in such patients, the diuresis produced has the relationship of a simple osmotic diuresis. The clinical implications are discussed.