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Circulation
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Circulation. 1950;2:438-440

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*Compound via MeSH
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*QUINIDINE
*QUINIDINE SULFATE

(Circulation. 1950;2:438.)
© 1950 American Heart Association, Inc.


Atypical Secondary or Symptomatic Thrombocytopenic Purpura Developing with the Use of Quinidine Sulfate

DONALD C. COLLINS M.D.

Quinidine sulfate, which has a very similar chemical structural formula to that of quinine bisulfate, may on a rare occasion be the etiologic causative agent of an atypical secondary or symptomatic thrombocytopenic purpura of serious degree. Fortunately, the withdrawal of the drug results in a rapid return to normal of the hematologic picture. A case report of such an occurrence is presented. Three additional case reports have been collected from the literature since 1941.