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(Circulation. 1959;20:875.)
© 1959 American Heart Association, Inc.

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A Simplified Indicator-Dilution Technic for the Localization of Left-to-Right Circulatory Shunts

An Experimental and Clinical Study of Intravenous Injection with Right Heart Sampling

EUGENE BRAUNWALD M.D.¹; WILLIAM W. PFAFF M.D.¹; ROBERT T. L. LONG M.D.¹; ANDREW G. MORROW M.D.¹

¹ From the Clinic of Surgery, National Heart Institute, Bethesda, Md.

Indicator-dilution curves recorded from a systemic artery after injection in the right heart may show the presence of a left-to-right shunt but will not localize it. Injections into the left side of the heart with arterial sampling or into the pulmonary artery with right heart sampling provide accurate and sensitive methods for localization but the technics are inconvenient and sometimes impossible to apply. A simplified indicator method for the localization of left-to-right circulatory shunts is described.