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(Circulation. 1960;21:522.)
© 1960 American Heart Association, Inc.

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Serum Lipoproteins in Patients with Intermittent Claudication and Myocardial Infarction

P. J. NESTEL M.B., B.S. (Sydney), MRACP¹

¹ From the Department of the James Stewart Professor of Medicine, University of Melbourne, Victoria, Australia.

The serum beta/alpha lipid ratios were estimated by electrophoresis in 4 groups of people. These comprised 44 male patients with intermittent claudication; 61 men who were matched for age with the previous group and who were clinically free of cardiovascular disease; 30 male patients who had recently had a myocardial infarction; and a further group of 30 male controls whose physical activity was limited by factors other than disease.

The highest mean serum beta/alpha lipid ratio was found among the patients with intermittent claudication and was very significantly higher than the ratios found among the other 3 groups. The difference in the ratios between the patients with myocardial infarction and the 2 control groups was not significant.

These differences and in particular the difference in the ratios between the patients with myocardial infarction and intermittent claudication are discussed.