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(Circulation. 1960;22:216.)
© 1960 American Heart Association, Inc.

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Effects of Acute Hypoxia on the Volume of Blood in the Thorax

H. W. FRITTS JR. M.D.¹; J. E. ODELL M.D.¹; P. HARRIS M.D.¹; E. W. BRAUNWALD M.D.¹; A. P. FISHMAN M.D.¹

¹ From the Department of Medicine, Columbia University, College of Physicians and Surgeons, and the Cardio-Pulmonary Laboratory of the First Medical and Chest Services (Columbia University Division), Bellevue Hospital, New York, N.Y.

Two different methods were used to study the effect of acute hypoxia on the volume of blood in the thorax. The first method entailed estimating the central blood volume by the Stewart-Hamilton dye-dilution technic; the second involved the use of a teeter-board. The 2 methods gave comparable results. Both indicated that the volume of blood in the thorax is not appreciably altered by hypoxia.