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(Circulation. 1960;22:913.)
© 1960 American Heart Association, Inc.

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I¹³¹-Diodrast Studies in Unilateral Renal Disease

JEROME B. BLOCK M.D.¹; GERALD J. HINE PH.D.¹; BELTON A. BURROWS M.D.¹; Valentine Bikerman B.S.¹

¹ From the Robert Dawson Evans Memorial, Massachusetts Memorial Hospitals, the Radioisotope and Medical Services, Boston Veterans Administration Hospital, and the Department of Medicine, Boston University School of Medicine, Boston, Mass.

A procedure utilizing I¹³¹-Diodrast with carrier Diodrast and a ratiometer has been evaluated for the early diagnosis of unilateral renal disease.

Relative differences in function between kidneys demonstrated by this procedure correlated well with findings at surgical exploration or autopsy.

In 3 patients with unilateral renal arterial stenosis who had normal intravenous pyelograms, I¹³¹-Diodrast results were abnormal.

Although normal I¹³¹-Diodrast results may rule out unilateral renal disease, an abnormal result with I¹³¹-Diodrast may be seen with any lesion resulting in urine flow differences between kidneys.

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