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Circulation. 1963;27:197-202

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(Circulation. 1963;27:197.)
© 1963 American Heart Association, Inc.


Spontaneous Calcific Embolization Associated with Calcific Aortic Stenosis

KEITH E. HOLLEY M.D.1; ROBERT C. BAHN M.D.1; DWIGHT C. McGOON M.D.1; HAROLD T. MANKIN M.D.1

1 From the Mayo Clinic and the Mayo Foundation, Rochester, Minnesota.

The problem of spontaneous calcific embolization was investigated at necropsy in 165 patients with calcific aortic stenosis. Minor coronary arteries contained calcific emboli in 18 patients (11 per cent), and major coronary arteries contained calcific emboli in 10 (6 per cent). Examination of the brain, kidney, and eye also disclosed spontaneous calcific emboli. In three instances of major coronary artery embolization, there was evidence of old silent infarction but no associated clinical disorder. Calcific embolization is apparently not rare in cases of calcific aortic stenosis, but this phenomenon does not appear to lead very often to extensive infarction or to clinically obvious disorders.




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