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(Circulation. 1963;27:339.)
© 1963 American Heart Association, Inc.

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Bronchoconstriction in the Presence of Pulmonary Embolism

VICTOR GUREWICH M.D.¹; DUNCAN THOMAS M.D.¹; MYRON STEIN M.D.¹; STANFORD WESSLER M.D.¹

¹ From the Medical Research Department of the Yamins Research Laboratories, Beth Israel Hospital, and the Department of Medicine, Harvard Medical School, Boston, Massachusetts.

In a group of seven patients with pulmonary embolism, evidence of bronchoconstriction was found. Heparin appeared to relieve partially the observed airway obstruction. A possible common mechanism for the initiation of intravascular coagulation and the production of bronchoconstriction was considered. When other causes can be eliminated, the detection of bronchoconstriction may serve as a useful index for the early recognition of pulmonary emboli.

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