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Circulation. 1963;27:1028-1033

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(Circulation. 1963;27:1028.)
© 1963 American Heart Association, Inc.


Results of Surgical Treatment of Incipient Stroke

JACK P. WHISNANT M.D.1; ROBERT G. SIEKERT M.D.1; PHILIP E. BERNATZ M.D.1; F. HENRY ELLIS JR. M.D.1

1 From the Mayo Clinic and the Mayo Foundation, Rochester, Minnesota.

Recently we have studied the role of surgical treatment of patients having occlusive cerebrovascular disease, particularly incipient stroke (or focal intermittent cerebrovascular insufficiency). This report concerns 35 pa-patients with incipient stroke in whom circulation was restored to normal by operation on an artery in an attempt to prevent transient ischemic episodes and cerebral infarction.

Since all of the patients were neurologically normal at the time of the surgical procedure, we were concerned primarily with the risk of [see tablein the PDF file] the procedure, particularly in terms of cerebral infarction. The operative mortality rate was 8.5 per cent (three patients). Six patients (17 per cent) sustained cerebral infarcts. Four of these had mild neurologic deficits, usually consisting of clumsiness and mildly reduced discriminatory sensation in one hand; one had a severe neurologic deficit, and one died. Evidence shows that at least some of these infarcts resulted from emboli arising from the operative site at the time of or shortly after the operation.

The results of long-term follow-up revealed that 66 per cent of the surgically treated patients were normal compared to 25 per cent of a contrast group; and 17 per cent of the treated patients had suffered cerebral infarcts compared to 40 per cent of the contrast group. The long-term results are thus similar to the immediate postoperative results. These findings simply indicate that an operated patient's prognosis was good over the long term if the cerebral ischemic episodes were relieved and if he sustained no complications from the surgical procedure.




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H. A. Shenkin, H. Haft, and F. M. Somach
Prognostic Significance of Arteriography in Nonhemorrhagic Strokes
JAMA, November 8, 1965; 194(6): 612 - 616.
[Abstract] [PDF]