This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by BRAUNSTEIN, H. Search for Related Content PubMed PubMed Citation Articles by BRAUNSTEIN, H.

(Circulation. 1963;28:1071.)
© 1963 American Heart Association, Inc.

---

Pathogenesis of Dissecting Aneurysm

HERBERT BRAUNSTEIN M.D.¹

¹ From the Department of Pathology, College of Medicine, University of Cincinnati and the Cincinnati General Hospital, Cincinnati, Ohio.

A group of 35 cases of dissecting aneurysm was studied both clinically and pathologically, in order to evaluate the role of alterations in the aortic wall in the pathogenesis of dissecting aneurysm. It was concluded that the commonly observed dilatation and hypertension promoted the initial tear by increasing the tension on the intima of the aorta. The usual cause of the aortic dilatation in this study was severe atherosclerosis; a much smaller group revealed an idiopathic medial degeneration; muscular lesions were regarded either as insignificant or as a result of the dissection. Although in many instances the initial perforation occurred through an atherosclerotic plaque, dissection proceeded readily through histologically normal media. Accordingly, it was concluded that the two histologic lesions encountered produced their effects largely by provoking dilatation of the aorta rather than by promoting propagation of the dissection.

This article has been cited by other articles:

				M. D. Kerstein, J. Kiev, and B. M. Levelo Familial Dissecting Aortic Aneurysm in the Absence of Marfan's Syndrome with Review of the Literature: Case Report Vascular and Endovascular Surgery, July 1, 1990; 24(6): 411 - 418. [Abstract] [PDF]

				M. Senoo, S. Teramoto, and H. Uchida Experimental Study of Ascending Aortic Dissection: Hemodynamics and Pathologic Aspects Vascular and Endovascular Surgery, September 1, 1989; 23(5): 381 - 397. [Abstract] [PDF]

				M. Mikail and S. Danesh Dissecting Aneurysm of Hepatic Artery: Report of a Fatal Case and Review of Literature Vascular and Endovascular Surgery, September 1, 1968; 2(3): 157 - 163. [PDF]

				F. Robicsek, J. P. Alexander, P. W. Sanger, F. H. Taylor, and V. Galucci Intermittent Occlusion of the Internal Carotid Artery by Detached Intima Angiology, January 1, 1965; 16(1): 18 - 20. [PDF]