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(Circulation. 1964;29:494.)
© 1964 American Heart Association, Inc.

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Successful Therapy of Prolonged Hypotension with an Adrenergic Beta-Receptor Blocking Agent

MYRON H. LURIA M.D.¹; ALBERT J. MILLER M.D.¹; BENJAMIN M. KAPLAN M.D.¹

¹ From the Cardiovascular Institute, Michael Reese Hospital and Medical Center, Chicago, Illinois.

Two patients with prolonged hypotension requiring continuous vasopressor therapy are described.

In both patients treatment with nethalide, a beta-receptor blocking agent, appeared clinically effective in allowing the withdrawal of metaraminol therapy and the maintenance of normotension. The results in these patients tend to fortify a hypothesis of peripheral adrenergic beta-receptor dominance in patients with prolonged hypotension.

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