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Circulation. 1964;30:109-113

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(Circulation. 1964;30:109.)
© 1964 American Heart Association, Inc.


Glossopharyngeal Neuralgia Associated with Bradycardia, Syncope, and Seizures

YIHONG KONG M.D.1; ALBERT HEYMAN M.D.1; MARK L. ENTMAN M.D.1; HENRY D. MCINTOSH M.D.1

1 From the Cardiovascular Laboratory and the Division of Neurology, Department of Medicine, Duke University Medical Center, Durham, North Carolina.

An unusual case of glossopharyngeal neuralgia associated with bradycardia, hypotension, syncope, and seizure is described. Our observations indicate that the cardiovascular components of this syndrome are probably due to stimulation of vagal centers by pain impulses arising from the glossopharyngeal area. Diphenylhydantoin therapy produced satisfactory relief of symptoms in this patient, probably by modification of the intensity of the neuralgic pain and thereby reducing the central vagal response.