This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via Google Scholar Google Scholar Articles by MATHUR, K. S. Articles by SAPRU, R. P. Search for Related Content PubMed PubMed Citation Articles by MATHUR, K. S. Articles by SAPRU, R. P.

(Circulation. 1964;30:694.)
© 1964 American Heart Association, Inc.

---

Lipid-Binding Capacity of Intimal Globulins in Human Aortic Atherosclerosis

K. S. MATHUR M.D.¹; R. D. SHARMA M.SC.¹; S. K. KASHYAP M.D.¹; R. P. SAPRU M.D.¹

¹ From the Department of Medicine, Sarojini Naidu Medical College, Agra, India.

One hundred forty-seven aortas obtained from medicolegal autopsies were studied. According to the extent of involvement of the intimal surface and the types of lesions, aortic atherosclerosis was classified as mild, moderate, and severe. The globulin content of the intima and its lipid-binding, and cholesterol-binding capacity were determined in each specimen.

No relation could be established between the globulin content of aortic intima and the degree of atherosclerosis. A direct correlation was observed, however, between the lipid-binding capacity and the cholesterol-binding capacity of the globulins and the severity of atherosclerosis, suggesting the possibility of a qualitative change in the globulins of the ground substance in atherosclerosis.