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Circulation. 1965;31:454-462

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(Circulation. 1965;31:454.)
© 1965 American Heart Association, Inc.


Hyperbaric Oxygen in Cardiovascular Disease

Potential Usages and Hazards

HERBERT A. SALTZMAN M.D.1

1 From the Department of Medicine, Duke University Medical Center, Durham, North Carolina.

In summary, hyperbaric oxygenation produces remarkable physiologic increases in oxygen transport to body tissues. However, potential benefit from hyperoxygenation in the treatment of ischemic disease appears dependent upon the presence of a partially intact capillary circulation. Improved means for prevention of oxygen toxicity and better technics of oxygen delivery to specific sites are required, if hyperbaric oxygenation is to fulfill present hopes for therapeutic application.