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(Circulation. 1966;33:302.)
© 1966 American Heart Association, Inc.

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Studies of the Retinal Circulation in Man

Observations on Vessel Diameter, Arteriovenous Oxygen Difference, and Mean Circulation Time

JOHN B. HICKAM M.D.¹ REGINA FRAYSER PH.D.¹

¹ From the Department of Medicine, Indiana University Medical Center, Indianapolis, Indiana.

By photographic techniques measurements have been made in the human retina of vessel size, arteriovenous oxygen difference across the retina, and mean retinal circulation time. By combination of these methods estimates can be made of relative changes in retinal blood flow rate and in the rate of oxygen delivery from the retinal vascular system. Observations are presented on the response of the normal and diseased retinal circulation to a variety of stimuli, particularly changes in blood oxygen and carbon dioxide tensions.

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