This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by YU, P. N. Articles by JAMES, D. H. Search for Related Content PubMed PubMed Citation Articles by YU, P. N. Articles by JAMES, D. H.

(Circulation. 1967;35:710.)
© 1967 American Heart Association, Inc.

---

Distensibility Characteristics of the Human Pulmonary Vascular Bed

Study of the Pressure-Volume Response to Exercise in Patients with and without Heart Disease

PAUL N. YU M.D.¹; GERALD W. MURPHY M.D.¹; BERNARD F. SCHREINER JR. M.D.¹; DOUGLAS H. JAMES M.D.¹

¹ From the Cardiopulmonary Unit, Department of Medicine, University of Rochester School of Medicine and Dentistry, and the Medical Clinics of Strong Memorial Hospital, Rochester, New York.

The changes in pulmonary blood flow, pressure, and volume during supine exercise are studied in seven patients without cardiovascular abnormality, 12 patients with aortic valve disease, 13 patients with mitral valve disease, and five patients with primary myocardial or pericardial disease. The degree of distensibility of the pulmonary vascular bed is assessed by the simultaneous changes in the magnitude of the pulmonary distending pressure (average of pulmonary artery and left atrial pressure) and of the pulmonary blood volume.

Key Words: Aortic valve disease • Constrictive pericarditis • Idiopathic cardiomyopathy • Pericardial effusion • Aortic aneurysm • Mitral valve disease • Cardiac catheterization

This article has been cited by other articles:

				G. Kovacs, A. Berghold, S. Scheidl, and H. Olschewski Pulmonary arterial pressure during rest and exercise in healthy subjects: a systematic review Eur. Respir. J., October 1, 2009; 34(4): 888 - 894. [Abstract] [Full Text] [PDF]

				D. B. Badesch, H. C. Champion, M. A. Gomez Sanchez, M. M. Hoeper, J. E. Loyd, A. Manes, M. McGoon, R. Naeije, H. Olschewski, R. J. Oudiz, et al. Diagnosis and assessment of pulmonary arterial hypertension. J. Am. Coll. Cardiol., June 30, 2009; 54(1 Suppl): S55 - S66. [Abstract] [Full Text] [PDF]