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(Circulation. 1951;4:387.)
© 1951 American Heart Association, Inc.

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A Study of the Effect of Procaine Amide Hydrochloride in Supraventricular Arrhythmias

MALCOLM C. MCCORD M.D.¹ JAMES T. TAGUCHI M.D.¹

¹ From the Department of Cardiology of the Veterans Administration Hospital, Dayton, Ohio, and the University of Cincinnati School of Medicine, Cincinnati, Ohio.

The effect of the intravenous administration of procaine amide in 25 patients with supraventricular arrhythmias is reported. The data, including six conversions of auricular fibrillation, indicate a pronounced effect of this drug on the auricles as well as on the heart as a whole. Special attention is directed to the finding of frequent and undesirable electrocardiographic and hypotensive effects of this drug.

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