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Circulation. 1969;40:315-325

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(Circulation. 1969;40:315.)
© 1969 American Heart Association, Inc.


Factors Related to ST-Segment Depression after Exercise in Middle-Aged Chinese Men

BENJAMIN N. CHAING M.D.1; E. RUSSELL ALEXANDER M.D.1; ROBERT A. BRUCE M.D.1; DONOVAN J. THOMPSON PH.D.1; NONG TING M.D.1

1 From the Department of Medicine, National Defense Medical Center, Taipei, Taiwan, Republic of China, and the Departments of Preventive Medicine and Medicine, University of Washington, Seattle, Washington.

Ninety-four or 7% of 1,346 healthy middle-aged Chinese men who underwent a graded treadmill test of maximal exercise showed post-exercise ST-segment depression. Stepwise linear discriminant function analysis showed that the major factors associated with this response were systolic blood pressures at maximal exercise, age, and certain resting ECG abnormalities, and to a lesser extent, systolic and diastolic pressure at rest, resting heart rate, and cigarette smoking. Hypertensive subjects showed at least a fourfold increase of post-exercise ST depression as compared with age-matched normotensive controls. Since coronary atherosclerosis is rare among Chinese, the study is of particular interest in demonstrating some factors related to ST depression after maximal exercise, particularly the effect of higher systemic pressure, in a group of middle-aged Chinese men.


Key Words: Hypertension • Taiwan cardiovascular study • Relative weight • Maximal systolic blood pressure • Maximal treadmill exercise




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