1 From the Departments of Medicine, University of Alabama Medical Center, Birmingham, Alabama, and the Ohio State University College of Medicine, Columbus, Ohio.
The relationships between the systolic time intervals determined from simultaneous recordings of the electrocardiogram, the phonocardiogram, the carotid arterial pulse tracing, and direct measures of left ventricular performance as assessed angiographically by measurement of left ventricular stroke volume (SV), end-diastolic volume (EDV), and ejection fraction (EF) were studied in 68 patients with a wide variety of cardiac diseases. The systolic intervals, the pre-ejection period (PEP), the left ventricular ejection time (LVET), and the ratio PEP/LVET, each correlated significantly with angiographically determined EF and EDV. Closest correlation was observed between PEP/LVET and EF (r = -0.90). The systolic intervals correlated only slightly with the angiographically determined SV. These data lend additional evidence supporting the use of systolic time intervals as a non-invasive measure of left ventricular performance in patients with cardiac disease.
Submitted on March 13, 1970
© 1970 American Heart Association, Inc.
The Relationship of Alterations in Systolic Time Intervals to Ejection Fraction in Patients with Cardiac Disease
Key Words: Angiocardiogram • Ratio of pre-ejection period to left ventricular ejection time • Non-invasive technic
Accepted on May 1, 1970
This article has been cited by other articles:
 |
|
 |
|
  P. Ritter, S. Cazeau, D. Gras, and J.-C. Daubert Cardiac resynchronization therapy implantation: a blend of skill and technology Eur. Heart J. Suppl., December 1, 2007; 9(suppl_I): I107 - I112. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Crisafulli, E. Salis, F. Tocco, F. Melis, R. Milia, G. Pittau, M. A. Caria, R. Solinas, L. Meloni, P. Pagliaro, et al. Impaired central hemodynamic response and exaggerated vasoconstriction during muscle metaboreflex activation in heart failure patients Am J Physiol Heart Circ Physiol, June 1, 2007; 292(6): H2988 - H2996. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Crisafulli, F. Melis, F. Tocco, U. M. Santoboni, C. Lai, G. Angioy, L. Lorrai, G. Pittau, A. Concu, and P. Pagliaro Exercise-induced and nitroglycerin-induced myocardial preconditioning improves hemodynamics in patients with angina Am J Physiol Heart Circ Physiol, July 1, 2004; 287(1): H235 - H242. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. Gonzalez, D. Dyar, and M. De Lange The Use of Myocardia1 Performance Index on Pediatric Heart Transplant Patients Journal of Diagnostic Medical Sonography, March 1, 1998; 14(2): 51 - 53. [Abstract] [PDF]
|
|
|
|
 |
|
 T. Hashimoto, N. Ohte, H. Narita, K. Kobayashi, and T. Fujinami Evaluation of a New Systolic Time Interval, the Q-V Peak: Effects of Heart Rate, Contractile State, and Loading Conditions in Dogs Angiology, August 1, 1992; 43(8): 685 - 692. [Abstract] [PDF]
|
|
|
|
|
|
L. Gould, C.V.R. Reddy, B. K. Singh, and Bujung Zen Cardiac Effects of Alcohol Angiology, November 1, 1980; 31(11): 753 - 759. [PDF]
|
|
|
|
|
|
S. Zoneraich, O. Zoneraich, J. J. Rhee, D. Jordan, and J. Appel Evaluating The Endurance Athlete's Heart: A Non-Invasive Graphic Study Angiology, April 1, 1979; 30(4): 223 - 239. [PDF]
|
|
|
|
|
|
T. Motomiya, T. Sano, and T. Shimamoto Effect of Isometric Handgrip On Systolic Time Intervals in Patients With Ischemic Heart Disease and Cyclic Amp Phosphodiesterase Inhibitor Pretreatment Angiology, May 1, 1977; 28(5): 346 - 350. [PDF]
|
|