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(Circulation. 1970;42:827.)
© 1970 American Heart Association, Inc.

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The Influence of Atrial Pressure on Cardiac Performance Following Myocardial Infarction Complicated by Shock

R. D. BRADLEY B.SC., M.B.¹; B. S. JENKINS M.B., M.R.C.P.¹; M. A. BRANTHWAITE M.R.C.P., F.F.A.R.C.S.¹

¹ From St. Thomas' Hospital, London, England.

Performance curves for both sides of the heart were derived in six patients with acute myocardial infarction complicated by cardiogenic shock. Stroke index and right and left ventricular stroke work index were related to mean atrial pressures which were lowered by venesection. Values for cardiac index, stroke index, and stroke work index were all low, and little change occurred with alterations in atrial pressures. The relationship of right and left atrial pressures to the genesis of pulmonary edema is discussed, and the effects of isoproterenol (isoprenaline) are described.

Key Words: Bilateral function curves • Pulmonary edema • Transseptal puncture • Isoproterenol

Submitted on May 19, 1970
Accepted on June 30, 1970