This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by BARNER, H. B. Articles by WILLMAN, V. L. Search for Related Content PubMed PubMed Citation Articles by BARNER, H. B. Articles by WILLMAN, V. L.

(Circulation. 1971;43:391.)
© 1971 American Heart Association, Inc.

---

Blood Flow in the Diabetic Leg

HENDRICK B. BARNER M.D.¹; GEORGE C. KAISER M.D.¹; VALLEE L. WILLMAN M.D.¹

¹ From the Department of Surgery, St. Louis University, and Unit II Surgery, John Cochran Veterans Administration Hospital, St. Louis, Missouri.

Femoropopliteal bypass grafting with reversed saphenous vein was performed in 47 nondiabetic and 27 diabetic extremities. Graft flow was measured with an electromagnetic flow probe before and after injection of 15 mg of papaverine into the graft. Basal flow (nondiabetic, 74 ± 6; diabetic, 76 ± 11 ml/min) was similar in the two groups. Peak flow was significantly higher in the nondiabetic group (217 ± 14 ml/min) than in the diabetic group (169 ± 18 ml/min, P < 0.05), and the outflow tract was significantly better in the nondiabetics (12.2 ± 0.5) than in the diabetics (8.6 ± 0.7, P < 0.001). When flow was related to the quality of the outflow tract, there was no significant difference between nondiabetics and diabetics. Diabetics with occlusive vascular disease have greater involvement of the tibial and peroneal arteries than do nondiabetics. Vascular reactivity is not significantly impaired, and arterial reconstruction should not be withheld on the basis of anteriolar-capillary involvement.

Key Words: Electromagnetic flowmeter • Occlusive arterial disease • Saphenous vein bypass graft

Submitted on September 11, 1970
Accepted on November 24, 1970

This article has been cited by other articles:

				J. C. Schramm, T. Dinh, and A. Veves Microvascular Changes in the Diabetic Foot International Journal of Lower Extremity Wounds, September 1, 2006; 5(3): 149 - 159. [Abstract] [PDF]

				T. L. Dinh and A. Veves Microcirculation in the Diabetic Foot: An Update International Journal of Lower Extremity Wounds, June 1, 2004; 3(2): 60 - 61. [PDF]

				N. L. Cantelmo, J. R. Snow, J. O. Menzoian, and F. W. LoGerfo Successful Vein Bypass in Patients With an Ischemic Limb and a Palpable Popliteal Pulse Arch Surg, February 1, 1986; 121(2): 217 - 220. [Abstract] [PDF]

				H. B. Barner, D. L. Kaminski, A. E. Ramey, P. J. Garvin, G. C. Kaiser, V. L. Willman, and J. E. Codd Extremity Salvage by Revascularization Vascular and Endovascular Surgery, March 1, 1979; 13(2): 95 - 103. [Abstract] [PDF]

				H. B. Barner Vasculitis in Maturity-Onset Diabetes Mellitus JAMA, June 7, 1976; 235(23): 2495 - 2495. [Abstract] [PDF]

				H. B. Barner, G. C. Kaiser, J. E. Codd, and V. L. Willman Coronary Graft Flow and Glucose Tolerance: Evidence Against the Existence of Myocardial Microvascular Disease Vascular and Endovascular Surgery, September 1, 1975; 9(4): 220 - 227. [PDF]

				H. B. Barner, D. L. Kaminski, J. E. Codd, G. C. Kaiser, and V. L. Willman Hemodynamics of Autogenous Femoropopliteal Bypass Arch Surg, August 1, 1974; 109(2): 291 - 293. [Abstract] [PDF]