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(Circulation. 1971;44:575.)
© 1971 American Heart Association, Inc.

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Determination of Left Ventricular Volumes by Ultrasound

NICHOLAS J. FORTUIN M.D.¹; WILLIAM P. HOOD JR. M.D.¹; M. EUGENE SHERMAN M.D.¹; ERNEST CRAIGE M.D.¹

¹ From the Medical Research Branch, Division of Health Effects Research, Air Pollution Control Office, Environmental Protection Agency, Department of Medicine, University of North Carolina School of Medicine, and the C. V. Richardson Laboratory, North Carolina Memorial Hospital, Chapel Hill, North Carolina 27514.

We compared dimensions of the left ventricular minor axis (S) measured at enddiastole (S_D) and end-systole (S_S) by echocardiography with dimensions and left ventricular volumes measured by biplane angiocardiography in 27 patients with diverse cardiac abnormalities. There were high correlations between echographic and angiographic ventricular minor-axis dimensions (r = 0.85 for S_D and 0.87 for S_S), between echographic dimensions and ventricular volumes (r = 0.84 for end-systolic volume [ESV] and S_S, 0.83 for end-diastolic volume [EDV] and S_D), and between the relative change in the echographic minor axis with systole (% S) and ejection fraction (r = 0.79). Regression formulae were derived from these relationships which allowed calculation of ventricular volumes from echo dimensions alone: ESV = 47 S_D—120, EDV = 59 S_D—153. These equations allowed relatively accurate prediction of volumes over a wide range of ventricular sizes. The use of a cube function of the echographic minor axis was an accurate predictor of volumes only in smaller ventricular chambers, but overestimated volumes in larger hearts.

Key Words: Angiocardiography • Minor-axis dimensions • Left ventricular geometry • Ejection fraction • Noninvasive techniques • Echocardiography

Submitted on March 23, 1971
Accepted on June 4, 1971

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