This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via Google Scholar Google Scholar Articles by LUEPKER, R. Articles by VARNAUSKAS, E. Search for Related Content PubMed PubMed Citation Articles by LUEPKER, R. Articles by VARNAUSKAS, E.

(Circulation. 1971;44:626.)
© 1971 American Heart Association, Inc.

---

Pulmonary Intravascular and Extravascular Fluid Volumes in Exercising Cardiac Patients

RUSSELL LUEPKER M.D.¹; BO LIANDER M.D.¹; MAGNUS KORSGREN M.D.¹; EDWARD VARNAUSKAS M.D.¹

¹ From the Department of Medicine I, Sahlgren's Hospital, University of Göteborg, Göteborg, Sweden.

Pulmonary extravascular (PEW) and intravascular (PBV) fluid volumes were measured during cardiac catheterization by a multiple indicator-dilution technique in 21 cardiac patients at rest and during exercise.

Increased PEW at rest was clearly related to increased left atrial and pulmonary artery pressures but not to blood flow or pulmonary vascular resistance.

Submaximal supine exercise produced increased intracardiac pressures and flow, with PEW and PBV significantly increased in most cases and stable in a few. Transudation at higher pulmonary capillary pressures and increased capillary recruitment were proposed to explain the increases in PEW during this short-term stress.

wo patients developed overt pulmonary edema with rales during exercise. These individuals are discussed separately.

Key Words: Diffusible indicators • Extravascular space • Pulmonary edema • Pulmonary circulation

Submitted on February 18, 1971
Accepted on June 17, 1971