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(Circulation. 1972;45:672.)
© 1972 American Heart Association, Inc.

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Abnormalities of the Mitral Valve in Endocardial Cushion Defects

MURRAY G. BARON M.D.¹

¹ From the Department of Radiology, The Mount Sinai Hospital and Mount Sinai School of Medicine of the City University of New York, New York, New York.

Absence of the atrioventricular septum and a cleft in the anterior leaflet of the mitral valve is characteristic of almost all anomalies resulting from maldevelopment of the endocardial cushions. These changes produce a specific angiocardiographic picture, characterized in systole by a scalloped right border of the left ventricular outflow tract, with a small lucent notch within it, and in diastole by a gooseneck appearance of the subaortic portion of the ventricle. This appearance is independent of the associated hemodynamic changes or the presence of other lesions. Because the angiocardiogram provides a direct demonstration of the underlying anatomic abnormalities, it is the most sensitive diagnostic method for the recognition of an endocardial cushion defect.

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