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(Circulation. 1973;47:509.)
© 1973 American Heart Association, Inc.

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Angina Pectoris in Men

Prognostic Significance of Selected Medical Factors

CHARLES W. FRANK M.D.; EVE WEINBLATT A.B.; SAM SHAPIRO B.S.

Prognosis of men whose first manifestation of coronary heart disease was angina without antecedent infarction was found to resemble closely that of men followed after an initial MI. Overall mortality over a period of 4.5 years following a baseline examination was the same in the two cohorts: 17.5%.

In both groups of men electrocardiographic abnormalities and blood pressure elevation identified subsets of coronary patients with a relatively poor prognosis, but the course of disease was apparently not influenced by the serum cholesterol level. Among the men with angina no relationship emerged between symptomatic status at time of baseline and risk of mortality in the ensuing observation period.

The findings are from the HIP (Health Insurance Plan of Greater New York) study of the incidence and prognosis of coronary heart disease, a prospective study of a general population of 110,000 men and women aged 25-64 years.

Key Words: Coronary heart disease • Serum cholesterol • ECG abnormalities • Hypertension • Myocardial infarction

Submitted on August 11, 1972
Accepted on November 13, 1972

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