| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
1 From the Department of Pediatries, Safdar Jung Hospital, New Delhi, India, and Department of Pediatries, St. Jude Children's Research Hospital, Memphis, Tennessee.
A prospective study was done to determine the clinical profile of first attacks of acute rheumatic fever in children in North India. Unlike other reports, the clinical profile described here closely resembles the spectrum prevalent in the West. Arthritis, the most common manifestation, was seen in 66.6% of the 102 patients, chorea in 20.7%, and carditis in 33.7%. Carditis was considered mild in 22 patients and severe in 12; a persistent elevation of sleeping pulse rate and mitral regurgitation was noted in each case. Patients with severe carditis also had significant cardiomegaly and apical mid-diastolic murmur. Two patients with severe carditis developed congestive heart failure; one of them had pericarditis as well. Murmur of aortic origin was not noted in this series. One patient with severe carditis died from the disease. Erythema marginatum was noted in two, both of whom had severe carditis. There were two instances of subcutaneous nodules, one with and one without carditis. The close similarity of these results with those in the West is attributed to the prospective design of the study, analysis of first attacks only and survey of a general pediatric population for all manifestations suggestive of the disease.
Submitted on June 1, 1973
© 1974 American Heart Association, Inc.
The Initial Attack of Acute Rheumatic Fever During Childhood in North India
A Prospective Study of the Clinical Profile
Key Words: Acute rheumatic fever • Subcutaneous nodules • Carditis • Arthritis • Erythema marginatum • Chorea • Streptococcus
Accepted on August 21, 1973
This article has been cited by other articles:
 |
|
 |
|
  G. Karthikeyan and B. M. Mayosi Is Primary Prevention of Rheumatic Fever the Missing Link in the Control of Rheumatic Heart Disease in Africa? Circulation, August 25, 2009; 120(8): 709 - 713. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J R Carapetis and B J Currie Rheumatic fever in a high incidence population: the importance of monoarthritis and low grade fever Arch. Dis. Child., September 1, 2001; 85(3): 223 - 227. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. R Carapetis and B. J Currie Rheumatic chorea in northern Australia: a clinical and epidemiological study Arch. Dis. Child., April 1, 1999; 80(4): 353 - 358. [Abstract] [Full Text]
|
|
|
|
|
|
R. S. Vasan, S. Shrivastava, M. Vijayakumar, R. Narang, B. C. Lister, and J. Narula Echocardiographic Evaluation of Patients With Acute Rheumatic Fever and Rheumatic Carditis Circulation, July 1, 1996; 94(1): 73 - 82. [Abstract] [Full Text]
|
|
|
|
 |
|
 Mohammend Abdulaziz Al-Sekait, Abdulrhman Abdulaziz Al-Sweliem, and M. Tahir Rheumatic Heart Disease in Schoolchildren in Westren District, Saudi Arabia Perspectives in Public Health, February 1, 1990; 110(1): 15 - 16. [Abstract]
|
|
|
|
 |
|
 E. C. McDANALD and M. H. WEISMAN Articular Manifestations of Rheumatic Fever in Adults Ann Intern Med, December 1, 1978; 89(6): 917 - 920. [Abstract] [PDF]
|
|
|
|
 |
|
 S. K. Sanyal, D. P. Mukerjee, and S. H. Ahmed Dermatoglyphic Alterations Associated With Acute Rheumatic Fever in Children Arch Pediatr Adolesc Med, July 1, 1978; 132(7): 692 - 695. [Abstract] [PDF]
|
|
|
|
|
|
G. BENZING III Prolonged PR Index in Rheumatic Fever Arch Pediatr Adolesc Med, May 1, 1976; 130(5): 467 - 468. [Abstract] [PDF]
|
|
|
|
|
|
S. K. Sanyal, M. K. Thapar, D. B. Sharma, and O. P. Shrivastava Atrioventricular Conduction in Children With Acute Rheumatic Fever Arch Pediatr Adolesc Med, May 1, 1976; 130(5): 473 - 476. [Abstract] [PDF]
|
|