This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by METCALFE, J. Articles by BURWELL, C. S. Search for Related Content PubMed PubMed Citation Articles by METCALFE, J. Articles by BURWELL, C. S.

(Circulation. 1952;5:518.)
© 1952 American Heart Association, Inc.

---

Studies in Experimental Pericardial Tamponade

Effects on Intravascular Pressures and Cardiac Output

JAMES METCALFE M.D.¹; JOHN W. WOODBURY M.D.¹; VICTOR RICHARDS M.D.¹; C. SIDNEY BURWELL M.D.¹

¹ From the Departments of Medicine and Physiology, Harvard Medical School and the Department of Medicine, Peter Bent Brigham Hospital, Boston, Mass.

As intrapericardial pressure is increased by the introduction of saline into the pericardial cavity, cardiac output falls. Intravascular pressures, arterial and venous, pulmonary as well as systemic, approach the same value. This equalization of intravascular pressure is due to the decreasing ability of the heart to maintain normal distribution of blood within the vessels.

This article has been cited by other articles:

				M. Hagiike, H. Maeta, H. Murakami, K. Okada, and H. Morita Mechanism of biphasic response of renal nerve activity during acute cardiac tamponade in conscious rabbits Am J Physiol Regulatory Integrative Comp Physiol, May 1, 1999; 276(5): R1232 - R1240. [Abstract] [Full Text] [PDF]