Circulation, Vol 51, 641-645, Copyright © 1975 by American Heart Association
HW Strauss, K Harrison, JK Langan, E Lebowitz and B Pitt
Following intravenous administration, the myocardial concentration of
tracer thallium-201, potassium-43, and rubidium-81 were determined in mice;
thallium was present in the greatest concentration in the myocardium (2.08%
compared 1.25% for potassium and 1.15% for rubidium at 10 minutes). The
regional myocardial distribution of thallium-201 was determined in dogs
under conditions of normal flow, and total occlusion, and compared with
potassium-43 (r=0.97). The regional distribution of thallium-201 was
compared to microspheres under conditions of partial occlusion and reactive
hyperemia (r=0.97). Thallium-201 was evaluated in a series of phantom
scans, which demonstrated that the low energy X-ray of thallium was
suitable for imaging. These results suggest that thallium-201 can be used
for the evaluation of the distribution of regional myocardial perfusion.
ARTICLES
Thallium-201 for myocardial imaging. Relation of thallium-201 to regional myocardial perfusion
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