Circulation, Vol 51, 1064-1070, Copyright © 1975 by American Heart Association
P Rigo, M Murray, DR Taylor, ML Weisfeldt, HW Strauss and B Pitt
One hundred and eleven patients with transmural (TMI) and 49 with
nontransmural myocardial infarction (NTMI) underwent hemodynamic
investigation within 24 hours of onset of symptoms. Patients with NTMI were
subdivided into those with ST-segment or T-wave changes alone with a normal
QRS complex (NTMI-A) and a group with QRS abnormalities that did not
satisfy the criteria for TMI (NTMI-B). Those with TMI had a significantly
higher peak creatine phosphokinase (CPK) than those with NTMI: 840 plus or
minus 99 and 336 plus or minus 69, respectively, P smaller than 0.05. There
was not difference in peak CPK between those with NTMI-A and B. The
incidence of arrhythmias and cardiac failure, and routine hemodynamic
findings except for left ventricular filling pressure were similar in those
with TMI and NTMI. There was not significant difference in in-hospital
mortality between those with TMI (22%) and NTMI (33%). There was however a
significant difference in in- hospital mortality between those with NTMI-A
(0%) and NTMI-B (27%, P smaller than 0.05). The late mortality in those
surviving their initial hospitalization was also not different between
those with TMI (18%) and NTMI (19%) during a mean follow-up period of 20.2
months. In contrast to the in-hospital mortality those with NTMI-A had a
late mortality similar to those with NTMI-B and those with TMI.
ARTICLES
Hemodynamic and prognostic findings in patients with transmural and nontransmural infarction
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