Circulation, Vol 52, 292-296, Copyright © 1975 by American Heart Association
CB Higgins and L Wexler
The dominance of the coronary arterial system was determined
angiographically in 75 adult patients with isolated aortic stenosis with or
without insufficiency, 25 adult patients with pure aortic insufficiency, 51
adult patients with combined aortic stenosis and mitral valve disease, and
44 children with bicuspid aortic valves. There was an unusually high
incidence of left dominance in adults with isolated aortic stenosis (36%)
and in children with bicuspid aortic valves (56.8%). These findings suggest
the existence of a variant developmental complex consisting of a bicuspid
aortic valve and reversal of dominance of the coronary arterial system.
Furthermore, it adds support to the concept that progressive stenosis of a
bicuspid aortic valve is frequently the etiology of isolated aortic
stenosis in adults.
ARTICLES
Reversal of dominance of the coronary arterial system in isolated aortic stenosis and bicuspid aortic valve
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