Circulation, Vol 53, 884-890, Copyright © 1976 by American Heart Association
M Nakazawa, RA Marks, J Isabel-Jones and JM Jarmakani
Right (RV) and left ventricular (LV) volume variables were calculated in 27
patients with pulmonary stenosis (PS) during routine cardiac
catheterization. These included 21 patients with isolated PS (group I) and
seven studies in six patients (group II) with PS and right-to-left atrial
shunt. Right and left ventricular volumes were calculated according to
Simpson's rule and the area length methods respectively. In group I, right
ventricular end-diastolic volume (RVEDV) was not different from normal,
RVEF (0.70 +/- 0.02) was significantly higher than normal, and right
ventricular stroke index (RVSI) (4.36/L/min/M2 +/- 0.23) was normal. The
RVEDV/LVEDV ratio was significantly less than normal (P=0.001). Multiple
regression analysis indicated that RVEDV (% of normal) decreased with both
age and severity of RV outflow obstruction (r=0.77). In group II, RVEDV and
RVSI were both less than normal (P less than 0.001), while RVEF was normal.
LVEDV in the group was slightly higher than normal (P=0.026) while LVEF was
less than normal (P=0.027) and resulted in normal LVSI. The data suggest
that RV and LV function in children with isolated PS are normal, and that
knowledge of the RV volume variables is not essential for the management of
these patients. In contrast, hearts of patients with PS and right-to-left
interatrial shunt have evidence that suggest depressed ventricular
function, and the quantitation of RV volume may be helpful in the
management of these patients.
ARTICLES
Right and left ventricular volume characteristics in children with pulmonary stenosis and intact ventricular septum
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