Circulation, Vol 55, 189-194, Copyright © 1977 by American Heart Association
WH Neches, SC Park, CC Lenox, JR Zuberbuhler, RD Siewers and RL Hardesty
From 1965 to 1974, 53 children with coarctation of the aorta (COA) and an
associated ventricular septal defect (VSD) underwent cardiac
catheterization. Thirty-one patients presented with congestive heart
failure. Twenty-five of 27 patients (92%) who underwent cardiac
catheterization under age 3 months had either systemic hypertension, a
systolic gradient across the coarctation greater than 20 mm Hg or both.
Pulmonary hypertension was present in all 25 patients. COA repair was
performed in 39 patients and there were seven deaths. Of the 32 survivors,
23 have no residual gradient; six are normotensive but have a mild residual
gradient; three are hypertensive or have a gradient greater than 20 mm Hg.
Repair of the VSD or pulmonary artery banding has been performed in 11 of
44 patients who survived infancy. Spontaneous closure of the VSD has
occurred in three cases and 25 patients have a small VSD that does not
warrant surgical repair. Surgical repair of COA during infancy may be
unavoidable but conservative medical management of the associated VSD is
often successful.
ARTICLES
Coarctation of the aorta with ventricular septal defect
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