Circulation, Vol 55, 242-246, Copyright © 1977 by American Heart Association
HC Cohen, I D'Cruz, ER Arbel, R Langendorf and A Pick
Eleven patients with tachycardia-dependent, bradycardia-dependent, or
"pseudobradycardia-dependent" bundle branch block (BBB) alternans were
studied. This classification is based on the following criteria: 1) When
alternans is initiated by a sudden acceleration in ventricular rate, or it
appears with aberration of the second beat after a pause, the alternans is
tachycardia-dependent and results from a 2:1 bidirectional block in the
affected bundle branch. 2) When alternans begins with the aberrant complex
terminating a pause it is bradycardia- dependent; such an alternans results
from alternating bundle branch cycle lengths and refractoriness, possibly
produced by alternating transseptal retrograde penetration of the affected
bundle branch. 3) In cases referred to as "pseudobradycardia-dependent BBB"
alternans, a change from alternans to persiscardia-dependent BBB"
alternans, a change from alternans to persistent BBB occurs as the cycle
lengthens; however, the disappearance of BBB with further increase of the
cycle length proves the tachycardia-dependence of the conduction defect.
ARTICLES
Tachycardia and bradycardia-dependent bundle branch block alternans: clinical observations
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