Circulation, Vol 55, 471-479, Copyright © 1977 by American Heart Association
JJ Gallagher, WC Sealy, RW Anderson, J Kasell, R Millar, RW Campbell, L Harrison, EL Pritchett and AG Wallace
Cryothermia, a new technique for definitive treatment of the pre-
excitation syndrome, is described in two patients. The first patient
presented with a normal P-R interval with a delta wave and reciprocating
tachycardia. Preoperative electrophysiologic study suggested a free-wall
atrioventricular connection on the left posterior atrioventricular (A-V)
groove. At surgery, epicardial mapping confirmed the site of pre-excitation
on the posterior left ventricular (LV) wall. An electrogram arising from
the accessory pathway (AP) was recorded at the site of earliest ventricular
activation. Interatrial delay combined with an apparently long accessory
pathway to the ventricle caused the P- R interval to appear normal. Local
pressure abolished pre-excitation. The site of early ventricular activation
was cooled to -60 degrees C with a specially designed cryoprobe. All
evidence of pre-excitation and arrhythmias disappeared. The second patient
presented with a refractory reciprocating tachycardia and was found to have
an AP in the septum capable of only retrograde conduction. Retrograde
conduction was abolished by applying a temperature of 0 degrees C to the
anulus at this site during tachycardia. Conduction over the AP and
reciprocating tachycardia returned with rewarming. Ablation of the AP was
obtained by applying a temperature of -60 degrees C for 90 seconds on two
occasions to the same area. The His bundle was not injured.
ARTICLES
Cryosurgical ablation of accessory atrioventricular connections: a method for correction of the pre-excitation syndrome
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