Circulation, Vol 55, 767-772, Copyright © 1977 by American Heart Association
WP Castelli, JT Doyle, T Gordon, CG Hames, MC Hjortland, SB Hulley, A Kagan and WJ Zukel
The relation between coronary heart disease (CHD) prevalence and fasting
lipid levels was assessed by a case-control study in five populations with
a total of 6859 men and women of black, Japanese and white ancestry drawn
from subjects aged 40 years and older from populations in Albany,
Framingham, Evans County, Honolulu and San Francisco. In each major study
group mean levels of high density lipoprotein (HDL) cholesterol were lower
in persons with CHD than in those without the disease. The average
difference was small -- typically 3-4 mg/dl -- but statistically
significant. It was found in most age-race-sex specific groups. The inverse
HDL cholesterol-CHD association was not appreciably diminished when
adjusted for levels of low density lipoprotein (LDL) cholesterol and
triglyceride. LDL, totoal cholesterol and triglycerides were directly
related to CHD prevalence; surprisingly, these findings were less uniformly
present in the various study groups than the inverse HDL cholesterol-CHD
association.
ARTICLES
HDL cholesterol and other lipids in coronary heart disease. The cooperative lipoprotein phenotyping study
This article has been cited by other articles:
 |
|
 |
|
  H. Komori, H. Arai, T. Kashima, T. Huby, T. Kita, and Y. Ueda Coexpression of CLA-1 and Human PDZK1 in Murine Liver Modulates HDL Cholesterol Metabolism Arterioscler. Thromb. Vasc. Biol., July 1, 2008; 28(7): 1298 - 1303. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. K. Arnett, A. E. Baird, R. A. Barkley, C. T. Basson, E. Boerwinkle, S. K. Ganesh, D. M. Herrington, Y. Hong, C. Jaquish, D. A. McDermott, et al. Relevance of Genetics and Genomics for Prevention and Treatment of Cardiovascular Disease: A Scientific Statement From the American Heart Association Council on Epidemiology and Prevention, the Stroke Council, and the Functional Genomics and Translational Biology Interdisciplinary Working Group Circulation, June 5, 2007; 115(22): 2878 - 2901. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. M. Reaven The Individual Components of the Metabolic Syndrome: Is There a Raison d'Etre? J. Am. Coll. Nutr., June 1, 2007; 26(3): 191 - 195. [Full Text] [PDF]
|
|
|
|
 |
|
 J. M S Lee and R. P Choudhury Prospects for atherosclerosis regression through increase in high-density lipoprotein and other emerging therapeutic targets Heart, May 1, 2007; 93(5): 559 - 564. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. M Reaven The metabolic syndrome: is this diagnosis necessary? Am. J. Clinical Nutrition, June 1, 2006; 83(6): 1237 - 1247. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. A. Reasner Niaspan(R): a powerful treatment option for 'diabetic dyslipidaemia' Eur. Heart J. Suppl., July 1, 2005; 7(suppl_F): F48 - F55. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Z. Li, R. Yang, G. Xu, and T. Xia Serum Lipid Concentrations and Prevalence of Dyslipidemia in a Large Professional Population in Beijing Clin. Chem., January 1, 2005; 51(1): 144 - 150. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. K. Welty, A. H. Lichtenstein, P. H. R. Barrett, G. G. Dolnikowski, and E. J. Schaefer Interrelationships Between Human Apolipoprotein A-I and Apolipoproteins B-48 and B-100 Kinetics Using Stable Isotopes Arterioscler. Thromb. Vasc. Biol., September 1, 2004; 24(9): 1703 - 1707. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. S. Cohn, C. Rodriguez, H. Jacques, M. Tremblay, and J. Davignon Storage of human plasma samples leads to alterations in the lipoprotein distribution of apoC-III and apoE J. Lipid Res., August 1, 2004; 45(8): 1572 - 1579. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. D. Curb, R. D. Abbott, B. L. Rodriguez, K. H. Masaki, R. Chen, J. S. Popper, H. Petrovitch, G. W. Ross, I. J. Schatz, G. C. Belleau, et al. High Density Lipoprotein Cholesterol and the Risk of Stroke in Elderly Men: The Honolulu Heart Program Am. J. Epidemiol., July 15, 2004; 160(2): 150 - 157. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. R Coughlin, L. Mawdsley, J. A Mugarza, P. M.A Calverley, and J. P.H Wilding Obstructive sleep apnoea is independently associated with an increased prevalence of metabolic syndrome Eur. Heart J., May 1, 2004; 25(9): 735 - 741. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. D. Curb, R. D. Abbott, B. L. Rodriguez, K. Masaki, R. Chen, D. S. Sharp, and A. R. Tall A prospective study of HDL-C and cholesteryl ester transfer protein gene mutations and the risk of coronary heart disease in the elderly J. Lipid Res., May 1, 2004; 45(5): 948 - 953. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. C. Carr, J. D. Brunzell, and S. S. Deeb Ethnic differences in hepatic lipase and HDL in Japanese, black, and white Americans: role of central obesity and LIPC polymorphisms J. Lipid Res., March 1, 2004; 45(3): 466 - 473. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M.J Chapman and M Caslake Non-high-density lipoprotein cholesterol as a risk factor: addressing risk associated with apolipoprotein B-containing lipoproteins Eur. Heart J. Suppl., March 1, 2004; 6(suppl_A): A43 - A48. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. W. Chisholm, J. Hong, S. A. Mills, and R. M. Lawn The LXR ligand T0901317 induces severe lipogenesis in the db/db diabetic mouse J. Lipid Res., November 1, 2003; 44(11): 2039 - 2048. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. N. Hewitt, W. C. Boon, Y. Murata, M. E. E. Jones, and E. R. Simpson The Aromatase Knockout Mouse Presents with a Sexually Dimorphic Disruption to Cholesterol Homeostasis Endocrinology, September 1, 2003; 144(9): 3895 - 3903. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Gulesserian and K. Widhalm Effect of a Rapeseed Oil Substituting Diet on Serum Lipids and Lipoproteins in Children and Adolescents with Familial Hypercholesterolemia J. Am. Coll. Nutr., April 1, 2002; 21(2): 103 - 108. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. R. Warnick, M. Nauck, and N. Rifai Evolution of Methods for Measurement of HDL-Cholesterol: From Ultracentrifugation to Homogeneous Assays Clin. Chem., September 1, 2001; 47(9): 1579 - 1596. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Perusse, A. Pascot, J.-P. Despres, C. Couillard, and B. Lamarche A new method for HDL particle sizing by polyacrylamide gradient gel electrophoresis using whole plasma J. Lipid Res., August 1, 2001; 42(8): 1331 - 1334. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. L. Klos, S. L. R. Kardia, R. E. Ferrell, S. T. Turner, E. Boerwinkle, and C. F. Sing Genome-Wide Linkage Analysis Reveals Evidence of Multiple Regions That Influence Variation in Plasma Lipid and Apolipoprotein Levels Associated With Risk of Coronary Heart Disease Arterioscler. Thromb. Vasc. Biol., June 1, 2001; 21(6): 971 - 978. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Georgopoulos, H.-Y. Kan, C. Reardon-Alulis, and V. Zannis The SP1 sites of the human apoCIII enhancer are essential for the expression of the apoCIII gene and contribute to the hepatic and intestinal expression of the apoA-I gene in transgenic mice Nucleic Acids Res., December 15, 2000; 28(24): 4919 - 4929. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. M. Vicari, G. J. Wan, A. M. Aura, C. M. Alexander, L. E. Markson, S. M. Teutsch, and for the Simvastatin Combined Hyperlipidemia Regist Use of Simvastatin Treatment in Patients With Combined Hyperlipidemia in Clinical Practice Arch Fam Med, September 1, 2000; 9(9): 898 - 905. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. E. Walden, B. M. Retzlaff, B. L. Buck, S. Wallick, B. S. McCann, and R. H. Knopp Differential Effect of National Cholesterol Education Program (NCEP) Step II Diet on HDL Cholesterol, Its Subfractions, and Apoprotein A-I Levels in Hypercholesterolemic Women and Men After 1 Year : The beFIT Study Arterioscler. Thromb. Vasc. Biol., June 1, 2000; 20(6): 1580 - 1587. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. J. Zema Gemfibrozil, nicotinic acid and combination therapy in patients with isolated hypoalphalipoproteinemia: a randomized, open-label, crossover study J. Am. Coll. Cardiol., March 1, 2000; 35(3): 640 - 646. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. M. Gotto Jr Prognostic and Therapeutic Significance of Low Levels of High-Density Lipoprotein Cholesterol: Current Perspectives Arch Intern Med, May 24, 1999; 159(10): 1038 - 1040. [Full Text] [PDF]
|
|
|
|
|
|
S. K Kamath, E. A Hussain, D. Amin, E. Mortillaro, B. West, C. T Peterson, F. Aryee, G. Murillo, and D L. Alekel Cardiovascular disease risk factors in 2 distinct ethnic groups: Indian and Pakistani compared with American premenopausal women Am. J. Clinical Nutrition, April 1, 1999; 69(4): 621 - 631. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y. Ueda, L. Royer, E. Gong, J. Zhang, P. N. Cooper, O. Francone, and E. M. Rubin Lower Plasma Levels and Accelerated Clearance of High Density Lipoprotein (HDL) and Non-HDL Cholesterol in Scavenger Receptor Class B Type I Transgenic Mice J. Biol. Chem., March 12, 1999; 274(11): 7165 - 7171. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. M. Grundy, G. J. Balady, M. H. Criqui, G. Fletcher, P. Greenland, L. F. Hiratzka, N. Houston-Miller, P. Kris-Etherton, H. M. Krumholz, J. LaRosa, et al. Primary Prevention of Coronary Heart Disease: Guidance From Framingham : A Statement for Healthcare Professionals From the AHA Task Force on Risk Reduction Circulation, May 19, 1998; 97(18): 1876 - 1887. [Full Text] [PDF]
|
|
|
|
|
|
A. Ritsch, H. Drexel, F. W. Amann, C. Pfeifhofer, and J. R. Patsch Deficiency of Cholesteryl Ester Transfer Protein : Description of the Molecular Defect and the Dissociation of Cholesteryl Ester and Triglyceride Transport in Plasma Arterioscler. Thromb. Vasc. Biol., December 1, 1997; 17(12): 3433 - 3441. [Abstract] [Full Text]
|
|
|
|
|
|
F.-Y. Jin, V. S. Kamanna, and M. L. Kashyap Niacin Decreases Removal of High-Density Lipoprotein Apolipoprotein A-I But Not Cholesterol Ester by Hep G2 Cells : Implication for Reverse Cholesterol Transport Arterioscler. Thromb. Vasc. Biol., October 1, 1997; 17(10): 2020 - 2028. [Abstract] [Full Text]
|
|
|
|
|
|
M. Laccotripe, S. C. Makrides, A. Jonas, and V. I. Zannis The Carboxyl-terminal Hydrophobic Residues of Apolipoprotein A-I Affect Its Rate of Phospholipid Binding and Its Association with High Density Lipoprotein J. Biol. Chem., July 11, 1997; 272(28): 17511 - 17522. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Kaplan, S. Kaplan, K. F. Marcoe, L. R. Sauvage, and W. P. Hammond Identification of Potential Predisposition to Clinical Atherosclerosis: A Clinical Concept Based on Integration of Significant Blood Parameters with Platelet Aggregation Scores Clinical and Applied Thrombosis/Hemostasis, July 1, 1997; 3(3): 174 - 182. [Abstract] [PDF]
|
|
|
|
|
|
B. Lamarche, S. Moorjani, B. Cantin, G. R. Dagenais, P. J. Lupien, and J.-P. Despres Associations of HDL2 and HDL3 Subfractions With Ischemic Heart Disease in Men: Prospective Results From the Quebec Cardiovascular Study Arterioscler. Thromb. Vasc. Biol., June 1, 1997; 17(6): 1098 - 1105. [Abstract] [Full Text]
|
|
|
|
|
|
P. N. M. Demacker, M. Hessels, H. Toenhake-Dijkstra, and H. Baadenhuijsen Precipitation methods for high-density lipoprotein cholesterol measurement compared, and final evaluation under routine operating conditions of a method with a low sample-to-reagent ratio Clin. Chem., April 1, 1997; 43(4): 663 - 668. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. E. Walden, B. M. Retzlaff, B. L. Buck, B. S. McCann, and R. H. Knopp Lipoprotein Lipid Response to the National Cholesterol Education Program Step II Diet by Hypercholesterolemic and Combined Hyperlipidemic Women and Men Arterioscler. Thromb. Vasc. Biol., February 1, 1997; 17(2): 375 - 382. [Abstract] [Full Text]
|
|
|
|
|
|
D. Kardassis, I. Tzameli, M. Hadzopoulou-Cladaras, I. Talianidis, and V. Zannis Distal Apolipoprotein C-III Regulatory Elements F to J Act as a General Modular Enhancer for Proximal Promoters That Contain Hormone Response Elements: Synergism Between Hepatic Nuclear Factor-4 Molecules Bound to the Proximal Promoter and Distal Enhancer Sites Arterioscler. Thromb. Vasc. Biol., January 1, 1997; 17(1): 222 - 232. [Abstract] [Full Text]
|
|
|
|
|
|
I. Tzameli and V. I. Zannis Binding Specificity and Modulation of the ApoA-I Promoter Activity by Homo- and Heterodimers of Nuclear Receptors J. Biol. Chem., April 5, 1996; 271(14): 8402 - 8415. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. Kardassis, M. Laccotripe, I. Talianidis, and V. Zannis Transcriptional Regulation of the Genes Involved in Lipoprotein Transport : The Role of Proximal Promoters and Long-range Regulatory Elements and Factors in Apolipoprotein Gene Regulation Hypertension, April 1, 1996; 27(4): 980 - 1008. [Full Text]
|
|
|
|
|
|
W. B. Kannel Clinical Misconceptions Dispelled by Epidemiological Research Circulation, December 1, 1995; 92(11): 3350 - 3360. [Abstract] [Full Text]
|
|
|
|
|
|
C. M. Burchfiel, A. Laws, R. Benfante, R. J. Goldberg, L.-J. Hwang, D. Chiu, B. L. Rodriguez, J. D. Curb, and D. S. Sharp Combined Effects of HDL Cholesterol, Triglyceride, and Total Cholesterol Concentrations on 18-Year Risk of Atherosclerotic Disease Circulation, September 15, 1995; 92(6): 1430 - 1436. [Abstract] [Full Text]
|
|
|
|
|
|
T. Katsuya, M. Horiuchi, Y.-D. I. Chen, G. Koike, R. E. Pratt, V. J. Dzau, and G. M. Reaven Relations Between Deletion Polymorphism of the Angiotensin-Converting Enzyme Gene and Insulin Resistance, Glucose Intolerance, Hyperinsulinemia, and Dyslipidemia Arterioscler. Thromb. Vasc. Biol., June 1, 1995; 15(6): 779 - 782. [Abstract] [Full Text]
|
|
|
|
 |
|
 J. M. Gaziano, J. E. Buring, J. L. Breslow, S. Z. Goldhaber, B. Rosner, M. VanDenburgh, W. Willett, and C. H. Hennekens Moderate Alcohol Intake, Increased Levels of High-Density Lipoprotein and Its Subfractions, and Decreased Risk of Myocardial Infarction N. Engl. J. Med., December 16, 1993; 329(25): 1829 - 1834. [Abstract] [Full Text]
|
|
|
|
 |
|
 J. J. Alexander, R. Miguel, and D. Graham High Density Lipoprotein Inhibits Low Density Lipoprotein Binding and Uptake by Bovine Aortic Endothelial Cells Angiology, December 1, 1990; 41(12): 1065 - 1069. [Abstract] [PDF]
|
|
|
|
 |
|
 W. C. Krupski and J. H. Rapp Smoking and Atherosclerosis Perspectives in Vascular Surgery and Endovascular Therapy, January 1, 1988; 1(1): 103 - 134. [PDF]
|
|
|
|
|
|
Y. Ueda, E. Gong, L. Royer, P. N. Cooper, O. L. Francone, and E. M. Rubin Relationship between Expression Levels and Atherogenesis in Scavenger Receptor Class B, Type I Transgenics J. Biol. Chem., June 30, 2000; 275(27): 20368 - 20373. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H.-Y. Kan, S. Georgopoulos, and V. Zannis A Hormone Response Element in the Human Apolipoprotein CIII (ApoCIII) Enhancer Is Essential for Intestinal Expression of the ApoA-I and ApoCIII Genes and Contributes to the Hepatic Expression of the Two Linked Genes in Transgenic Mice J. Biol. Chem., September 22, 2000; 275(39): 30423 - 30431. [Abstract] [Full Text] [PDF]
|
|