This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Wackers, F. J. Articles by Wellens, H. Search for Related Content PubMed PubMed Citation Articles by Wackers, F. J. Articles by Wellens, H.

Circulation, Vol 56, 72-78, Copyright © 1977 by American Heart Association

ARTICLES

Location and size of acute transmural myocardial infarction estimated from thallium-201 scintiscans. A clinicopathological study

FJ Wackers, AE Becker, G Samson, EB Sokole, JB van der Schoot, AJ Vet, KI Lie, D Durrer and H Wellens

A clinicopathological study was performed in 23 patients who died from acute transmural myocardial infarction and who had been studied with thallium-201 during the acute phase. Twenty patients died within five days and three later than five days after scintigraphy. The scintigraphic location and the estimated size of infarction in vivo were correlated with postmortem findings. There was good agreement in 91% between scintigraphic and postmortem location of infarction and in 70% between the ECG and postmortem findings. The size of infarction as determined from computer-processed schematic drawings of postmortem slices of the heart correlated well with the size determined from processed schematic drawings of the scintiscans (r = 0.91 for anterior infarction, r = 0.97 for inferior infarction, r = 0.86 for anterior- inferior infarction). It is concluded that thallium-201 scintigraphy provided more precise location of infarction than the ECG and that the size of the scintigraphically abnormal area reflected the extent of necrotic myocardium.

This article has been cited by other articles:

				L. Stegger, A.-N. Hoffmeier, K. P. Schafers, S. Hermann, O. Schober, M. A. Schafers, and G. Theilmeier Accurate Noninvasive Measurement of Infarct Size in Mice with High-Resolution PET J. Nucl. Med., November 1, 2006; 47(11): 1837 - 1844. [Abstract] [Full Text] [PDF]

				R. Medrano, R. W. Lowry, J. B. Young, D. G. Weilbaecher, L. H. Michael, I. Afridi, Z.-X. He, J. J. Mahmarian, and M. S. Verani Assessment of Myocardial Viability With 99mTc Sestamibi in Patients Undergoing Cardiac Transplantation: A Scintigraphic/Pathological Study Circulation, September 1, 1996; 94(5): 1010 - 1017. [Abstract] [Full Text]

				B. L. Zaret and F. J. Wackers Nuclear Cardiology- First of Two Parts N. Engl. J. Med., September 9, 1993; 329(11): 775 - 783. [Full Text]

				R. E. RUDE, J. E. MULLER, and B. EUGENE Efforts to Limit the Size of Myocardial Infarcts Ann Intern Med, December 1, 1981; 95(6): 736 - 761. [Abstract] [PDF]

				A. S. Iskandrian, L. Wasserman, and B. L. Segal Thallium 201 Myocardial Scintigraphy: Advantages and Limitations Arch Intern Med, March 1, 1980; 140(3): 320 - 327. [Abstract] [PDF]

				E. H. Botvinick Myocardial Perfusion Scintigraphy Arch Intern Med, February 1, 1980; 140(2): 169 - 171. [Abstract] [PDF]

				M. B. Bodenheimer, V. S. Banka, C. M. Fooshee, and R. H. Helfant Extent and Severity of Coronary Heart Disease: Determinations by Thallous Chloride Tl 201 Myocardial Perfusion Scanning and Comparison With Stress Electrocardiography Arch Intern Med, June 1, 1979; 139(6): 630 - 634. [Abstract] [PDF]

				H. J. BERGER, A. GOTTSCHALK, and B. L. ZARET Dual Radionuclide Study of Acute Myocardial Infarction: Comparison of Thallium-201 and Technetium-99m Stannous Pyrophosphate Imaging in Man Ann Intern Med, February 1, 1978; 88(2): 145 - 154. [Abstract] [PDF]