Circulation, Vol 56, 914-917, Copyright © 1977 by American Heart Association
JS Colocousis, LL Huntsman and PW Curreri
The purpose of this study was to conduct a controlled evaluation of the
continuous-wave Doppler technique for the estimation of stroke volume
changes. Six anesthetized dogs were studied. Aortic blood velocity was
recorded from the suprasternal notch by a special continuous-wave Doppler
unit. Cardiac output was varied by fluid infusion and exsanguination, and
over 300 simultaneous records of aortic blood velocity and thermodilution
cardiac output were taken. Average stroke volume and average systolic
velocity integral (SVI), the area under the Doppler velocity curve were
calculated. The relationship of SVI to stroke volume was evaluated for each
animal using linear regression. Average results were: correlation
coefficient 0.95 +/- 0.04 SD; y- intercept 0.38 +/- 0.14 cm(SD); standare
error of fit 0.29 +/- 0.03 cm (SD). These data show that the systolic
integral of aortic blood velocity was essentially directly proportional to
stroke volume, even over a six-fold range. Thus, this technique will
provide an accurate non-invasive estimate of changes in stroke volume.
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