This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Brenner, J. I. Articles by Waugh, R. A. Search for Related Content PubMed PubMed Citation Articles by Brenner, J. I. Articles by Waugh, R. A.

Circulation, Vol 57, 122-127, Copyright © 1978 by American Heart Association

ARTICLES

Effect of phasic respiration on left ventricular dimension and performance in a normal population. An echocardiographic study

JI Brenner and RA Waugh

Echocardiographic examination of the left ventricle (LV) in 30 normal subjects, 5 to 47 years of age, was performed in order to analyze the effects of phasic respiration on LV dimensions and derived LV function. Peak expiratory and peak inspiratory LV diastolic and systolic dimensions were measured and extrapolated to volume estimates using a standard formula. Although there was wide variation in the individual measurements, and particularly in systolic dimension, the mean peak inspiratory diastolic dimension, derived diastolic volume, and stroke volume all decreased significantly (P less than 0.001); a smaller decrease in ejection fraction was seen (P less than 0.02), while the changes in mean end-systolic dimension and end-systolic volume were not significant. While these observed changes may reflect a true physiologic variation, an artifactual component cannot be excluded. Regardless of their physiologic significance, however, these data show that the effect of phasic respiration is a factor to be considered in correlative echocardiographic studies of LV function in both normal and, possibly, pathologic cardiovascular conditions.

This article has been cited by other articles:

				Y. Cottin, C. Touzery, F. Guy, A. Lalande, O. Ressencourt, S. Roy, P. M. Walker, P. Louis, F. Brunotte, and J. E. Wolf MR Imaging of the Heart in Patients after Myocardial Infarction: Effect of Increasing Intersection Gap on Measurements of Left Ventricular Volume, Ejection Fraction, and Wall Thickness Radiology, November 1, 1999; 213(2): 513 - 520. [Abstract] [Full Text]

				V. S. Lee, N. M. Rofsky, G. A. Krinsky, D. H. Stemerman, and J. C. Weinreb Single-Dose Breath-hold Gadolinium-enhanced Three-dimensional MR Angiography of the Renal Arteries Radiology, April 1, 1999; 211(1): 69 - 78. [Abstract] [Full Text]

				J. N. Amoore and W. P. Santamore A Simulation Study of Factors Influencing Respiratory Variations in Blood Flow with Special Reference to the Effects of the Phase Delay Between the Respiratory and Cardiac Cycles SIMULATION, April 1, 1996; 66(4): 229 - 241. [Abstract] [PDF]

				R. J. Sarma, C. A. Stewart, I. S. Gilgoff, and J. R. Bach Cardiovascular Considerations in the Management of Duchenne Muscular Dystrophy Neurorehabil Neural Repair, January 1, 1992; 6(2): 113 - 119. [Abstract] [PDF]