Circulation, Vol 57, 137-139, Copyright © 1978 by American Heart Association
JE Muller and SJ Gunther
A case is described in which nifedipine, a new coronary vasodilator, was
effective in relieving attacks of Prinzmetal's angina unresponsive to
conventional therapy. The extreme frequency of the anginal attacks provided
evidence that lower doses of nifedipine lost their effectiveness
approximately 4 hours after administration. A month after initiation of
nifedipine, nitrates were withdrawn since they had been ineffective in
controlling the attacks. A myocardial infarction occurred immediately,
presumably due to coronary spasm.
ARTICLES
Nifedipine therapy for Prinzmetal's angina
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