Circulation, Vol 57, 1022-1025, Copyright © 1978 by American Heart Association
WD Edwards, DS Leaf and JE Edwards
Among 119 cases of fatal dissecting aneurysm of the aorta, exclusive of
those iatrogenically caused or associated with arachnodactyly or aortic
stenosis, there were observed 11 cases of congenital bicuspid aortic valve
(9%). The ages ranged from 17 to 69 years, five of the patients being 29
years old or younger. Among the latter, three had coarctation of the aorta
and one had Turner's syndrome without coarctation. In one of the older
patients, aortic insufficiency was present. Hypertension was either
established or inferred from cardiac weight in 73% of the cases. In each
case, cystic medial necrosis of the aorta was present. Prolapse of valves
other than the aortic was observed in 45% of the cases with bicuspid aortic
valve. Compared to an estimated incidence of bicuspid aortic valve of about
1 to 2% in the population, the high incidence among subjects with
dissecting aneurysm suggests a causative relationship between bicuspid
aortic valve and aortic dissecting aneurysm.
ARTICLES
Dissecting aortic aneurysm associated with congenital bicuspid aortic valve
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|
|
|
|
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|
|
|
|
 |
|
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|
|
|
|
|
|
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|
|
|
|
 |
|
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|
|
|
|
 |
|
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|
|
|
|
 |
|
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|
|