Circulation, Vol 57, 1205-1213, Copyright © 1978 by American Heart Association
BJ Maron, WH Merrill, PA Freier, KM Kent, SE Epstein and AG Morrow
Long-term results of operation for IHSS were reviewed in 124 patients
operated upon between 1960 and 1975. Most patients improved symptomatically
and manifested marked reduction in LV outflow gradient at rest
postoperatively. However, ten (8%) patients died of causes related to
operation, 14 (12%) had persistent or recurrent severe functional
limitation, and 11 (9%) died up to 13 years postoperatively due to
hypertrophic cardiomyopathy. Overall annual mortality rate was 3.5% and was
1.8% for late deaths alone. Of 11 late postoperative deaths, six were
sudden and five were due to chronic heart failure. Atrial fibrillation was
significantly more common in patients who died late postoperatively than in
survivors. Nine of the 11 late deaths had associated medical problems that
may have contributed to their outcome. In conclusion, long-lasting clinical
improvement occurred in most patients who survived operation for IHSS.
However, 12% of patients deteriorated clinically over the 5.2 year average
follow-up, and there is continued, small annual mortality.
ARTICLES
Long-term clinical course and symptomatic status of patients after operation for hypertrophic subaortic stenosis
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