Circulation, Vol 58, 940-946, Copyright © 1978 by American Heart Association
Electrophysiological demonstration of concealed conduction in the human atrium
RJ Sung, RJ Myerburg and A Castellanos
In the course of electrophysiological evaluation of six patients with sick
sinus syndrome, two patients with chronic conduction system disease and
four patients with paroxysmal supraventricular tachycardia or atrial
flutter-fibrillation, the phenomenon of concealed conduction within the
atrium (At) was repeatedly observed. One pair of intracardiac electrodes
was used to deliver electrical stimulus (St) to the high right At and two
additional pairs of electrodes were utilized to record high right and low
septal right atrial electrograms. The interelectrode distances were 10 mm
apart. In all 12 patients, high right atrial capture could be accomplished
at a pacing rate of greater than or equal to 200 beats/min. Concealed
intra-atrial conduction was evident when the intra-atrial conduction time
of the propagated St during 2:1 St-At block was more than 40 msec longer
than that during 1:1 St-At conduction at half the St frequency. This
indicated that the nonpropagated St during 2:1 St-At block partially
penetrated the At and in turn, delayed conduction of the subsequently
propagated St. Futher observations revealed that a gradual increase in the
St frequency resulted in a progressive prolongation of the intra-atrial
conduction time and a shifting of 2:1 to 3:1 St-At block (alternating
Wenckebach periodicity in the At) in five patients. These findings clearly
demonstrate the occurrence of concealed conduction in the human At.