This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Darsee, J. R. Articles by Lesser, L. E. Search for Related Content PubMed PubMed Citation Articles by Darsee, J. R. Articles by Lesser, L. E.

Circulation, Vol 59, 619-622, Copyright © 1979 by American Heart Association

ARTICLES

Prevalence of mitral valve prolapse in presumably healthy young men

JR Darsee, JR Mikolich, NB Nicoloff and LE Lesser

We determined the prevalence of mitral valve prolapse (MVP) in presumably healthy young men by studying 107 male house officers and medical students with cardiac auscultation in the supine, sitting and standing positions. Echocardiograms were performed at rest in the supine position before and after amyl nitrite inhalation and were obtainable in 101 subjects. Eleven of the 101 subjects had abnormal findings on auscultation: four had an isolated click and seven had a click and late systolic murmur. Correlation of the independent auscultatory and echocardiographic data in the 101 subjects showed that all seven of the subjects with a click and a murmur had echocardiographic evidence of prolapse. None of the 90 subjects with normal auscultation or the four with an isolated click had an abnormal echocardiogram. All seven subjects with MVP had thoracic skeletal abnormalities, but only one was symptomatic. These data suggest that the prevalence of MVP in healthy young males is similar to the reported 6-10% prevalence in healthy young females.

This article has been cited by other articles:

				C. J. Lavie, B. K. Khandheria, J. B. Seward, A. J. Tajik, C. L. Taylor, and D. J. Ballard Factors Associated With the Recommendation for Endocarditis Prophylaxis in Mitral Valve Prolapse JAMA, December 15, 1989; 262(23): 3308 - 3312. [Abstract] [PDF]

				A. F. Heck 35th Annual Meeting -- American College of Angiology Orlando, Florida -- October, 1988 Symposium Proceedings: Neurologic Aspects of Mitral Valve Prolapse Angiology, August 1, 1989; 40(8): 743 - 751. [Abstract] [PDF]

				F. H. Zimmerman and A. H. Mogtader Ruptured Chordae Tendineae and Acute Pulmonary Edema Induced by Exercise: Occurrence in a Young Man With Mitral Valve Prolapse JAMA, August 14, 1987; 258(6): 812 - 813. [Abstract] [PDF]

				L. Gould and C. Gopalaswamy Mitral Valve Prolapse Angiology, May 1, 1984; 35(5): 290 - 299. [PDF]

				E. Macieira-Coelho, F. Pais, F. Monteiro, J. M. da Conceicao, M. Garcia Alves, and L. Pereira Barlow's Syndrome Associated with Coronary Fistula Angiology, October 1, 1983; 34(10): 688 - 692. [Abstract] [PDF]

				R. B. DEVEREUX, W. T. BROWN, R. KRAMER-FOX, and I. SACHS Inheritance of Mitral Valve Prolapse: Effect of Age and Sex on Gene Expression Ann Intern Med, December 1, 1982; 97(6): 826 - 832. [Abstract] [PDF]

				D. G. McNamara Idiopathic Benign Mitral Leaflet Prolapse: The Pediatrician's View Arch Pediatr Adolesc Med, February 1, 1982; 136(2): 152 - 156. [Abstract] [PDF]

				S. Wessler Drug Prophylaxis for Arterial Thromboembolism--1981 JAMA, November 27, 1981; 246(21): 2484 - 2487. [Abstract] [PDF]

				K. B. Desser, S. I. Bokhari, A. Benchimol, and D. Romney All in the Family: Matrimonial Mitral Valve Clicks Angiology, May 1, 1981; 32(5): 355 - 360. [Abstract] [PDF]

				M. D. Cheitlin and R. C. Byrd The Click-Murmur Syndrome: A Clinical Problem in Diagnosis and Treatment JAMA, April 3, 1981; 245(13): 1357 - 1361. [Abstract] [PDF]

				R. B. Whiting Ventricular Premature Contractions Which Should Be Treated? Arch Intern Med, November 1, 1980; 140(11): 1423 - 1426. [Abstract] [PDF]