Circulation, Vol 59, 714-721, Copyright © 1979 by American Heart Association
J Leppo, T Yipintsoi, R Blankstein, R Bontemps, LM Freeman, L Zohman and J Scheuer
Thirty patients with triple-vessel coronary artery disease proven by
angiography, symptomatic angina and a positive ECG stress test were
evaluated with thallium-201 (201TI) scintigraphy. Twenty patients also had
aortocoronary saphenous vein bypass surgery; 15 of them had repeat
noninvasive evaluation. Seventy percent of these patients showed ischemia
by 201TI scintigraphy, of which one-half returned to normal after surgery.
Postoperative reversion of the ECG stress test together with 201TI
stress/reperfusion imaging correlated well with the completeness of
surgical revascularization. We could not explain the prevalence (80%) of
infarcts detected by 201TI in this group, of which 76% could be
anatomically correlated to epicardial scars. The positivity of infarcts by
201TI exceeded that predicted by previous history of infarction, Q waves on
resting ECG or ventriculographic akinesis. These observations suggest that
201TI scintigraphy is a useful noninvasive tool in the follow-up and
understanding of patients with coronary heart disease. These conclusions
also support the concept that 201TI stress imaging need not have the
identical connotation as the ECG stress test.
ARTICLES
Thallium-201 myocardial scintigraphy in patients with triple-vessel disease and ischemic exercise stress tests
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